814 SLEEP DISORDERS AND DYSBIOSIS: CULPRITS IN CARDIOVASCULAR DISEASES
نویسندگان
چکیده
Abstract Introduction Primary prevention of cardiovascular disease, the leading cause death worldwide, has become a mainstay in addressing this considerable global challenge. It clear that gut microbiome plays vital role human metabolism, immunity, and reactions to diseases, including disease. Growing evidence suggests sleep quality can be influenced by Gut Microbiome (GM), since probiotic supplementation been found improve subjective healthy. Disruption sleep/wake functions associated with both short (increased stress responsivity or psychosocial issues) long term health consequences, cancer diseases. Emerging disturbance circadian rhythm, which incorporates essential physiological humoral 24-hour cycle, could an understudied risk factor for While impaired is significant contributor rhythm disturbance, regarding interventions their effect on events lacking. We conduct literature review synthesize body interaction between GM order achieve robust broad conclusions implications system. Methods reviewed relationship sleep, from January 2017 up until August 2022. Results The influence through bidirectional communication channel linking brain gut, Brain-Gut-Microbiome Axis (BGMA). Many authors have described several underlying factors involved sleep-disorder, such as immune system, vagus nerve (VN), neuroendocrine bacterial metabolites. Furthermore, targeting proved beneficial amelioration problems: gamma-amino butyric acid (GABA) produced intestinal microbiota may central nervous system VN some studies reported Conclusions Sleep constitute novel target preventive intervention. More research well-designed are needed better evaluate multi-directional diet CVD. From our analysis provides wide range potential therapeutic targets. Challenges ahead include development reversing dysbiosis, at early stage, combined good behavior, open new horizons prevent
منابع مشابه
Sleep and Cardiovascular Disorders
Sleep is essential for life and for physical, mental and emotional well being. Sleep must be of good quantity and quality. There is a close association between sleep and cardiovascular system. Cardiac functions in sleep are under control of autonomic nervous system activity, which in turn is dictated by brain states. NREM sleep is associated with relative cardiac and autonomic stability. There ...
متن کاملSleep deprivation, sleep apnea and cardiovascular diseases.
Sleep dramatically influences cardiovascular regulation. Changes in sleep duration or quality as seen in sleep disorders may prevent blood pressure to fall during sleep as expected in human physiology. This supports the increased prevalence of hypertension and drug-resistant hypertension in those with sleep loss. Other cardiovascular outcomes i.e. coronary lesions seem to be associated with sle...
متن کاملBridging the Gap between Gut Microbial Dysbiosis and Cardiovascular Diseases
The human gut is heavily colonized by a community of microbiota, primarily bacteria, that exists in a symbiotic relationship with the host and plays a critical role in maintaining host homeostasis. The consumption of a high-fat (HF) diet has been shown to induce gut dysbiosis and reduce intestinal integrity. Recent studies have revealed that dysbiosis contributes to the progression of cardiovas...
متن کاملSleep Apnea and Cardiovascular Diseases
1 Department of Pneumology, La Paz University Hospital, Madrid, Spain 2 Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdiPAZ), Autónoma de Madrid University, Madrid, Spain 3 Department of Pneumology, Rı́o Hortega Hospital, Valladolid University, Valladolid, Spain 4Department of Pneumology, Santiago de Compostela Hospital, Santiago de Compostela Universidad, A Coruña, Sp...
متن کاملSurvey on the Effects of Sleep Disorders on Cardiovascular Index and Exercise Performance in Diabetic Patients
Background: Diabetes mellitus is one of the leading causes of death in the world as a result of a defect in the secretion or function of insulin. Sometimes insomnia can be a complication of diabetes or it can be a factor in diabetes. On the other hand, impairment in sleep quality is associated with increased risk of diabetes and mortality. Some studies have also shown that sleep deprivation has...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2022
ISSN: ['1520-765X', '1554-2815']
DOI: https://doi.org/10.1093/eurheartjsupp/suac121.709